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Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases

Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-B activation in a cerebral ischemia mouse model

[The study of insulin resistance and leptin resistance on the model of simplicity obesity rats by curcumin]

Furthermore, strain-specific effects and gut microbiota-dependent response prediction require validation in precision medicine trials

43 DixonD

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