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Daily injections of THC (2 mg/kg ) caused locomotor depression in both male and female rats dosed during early adolescence but only in female animals dosed during late adolescence (Harte et al., 2010)

For example, activation of the limbic and paralimbic systems, which are responsible for behavioral and emotional responses, are thought to contribute to distress signaling and complications of tinnitus, such as cognitive, mood, and sleep disorders, in some individuals

R.LydenP.BlackwellL.AlbersG.BluhmkiE.et al

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Lower concentrations require larger injection volumes, but for subcutaneous administration, volumes up to 0.5mL per site are well-tolerated in most research models

Long noncoding RNA LINC00518 induces radioresistance by regulating glycolysis through an miR-33a-3p/HIF-1 negative feedback loop in melanoma