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The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain treg cell activation and suppression of antitumor immunity

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The pixels of inflamed edematous regions with high signal intensity in the axial image were measured using the Image J 1.52a software (National Institutes of Health, USA), and a comparative analysis between the control group and Si-based agent-treated group was conducted

2.5.3 Necroptosis Necroptosis is a programmed cell death process dependent on the receptor-interacting serine/threonine-protein kinase 1/receptor-interacting serine/threonine-protein kinase 3/mixed lineage kinase domain-like pseudokinase (RIPK1/RIPK3/MLKL) axis

From day 8 to day 14, cells were cultured under normoxia in RPMI 1640 medium (Invitrogen) supplemented with 2 mM Gluta-MAX, 1 B-27 supplement (Invitrogen) and 50 g ml 1 AA

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