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On the other hand, an increased iodine intake in an iodine-deficient population is associated with a small increase in the prevalence of a subclinical hypothyroidism and thyroid autoimmunity [52]

81 Studies have revealed that abnormal purine metabolism may exacerbate the inflammatory response in ARDS patients (Figure 4)

A study found that the NRF2-KEAP1 complex keeps shuttling constantly between the cytoplasm and the nucleus, and in the nucleus, the nuclear protein prothymosin competes for NRF2 binding to KEAP1 and enables the liberated NRF2 to activate NRF2 target genes [15]

Available from: www.thesgc.org/science/imp Smith S

Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase