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Theranostics 10:73847400 Pieniazek A, Kopera M, Gwozdzinski L, Gwozdzinski K (2022) Indoxyl sulfate induces oxidative changes in plasma and hemolysate

Since previous studies reported aberrant mitochondrial morphology in AS [10], and we previously observed that Ube3a -null MEFs exhibit altered mitochondria-associated pathways [29, 30], we posited that the AS mitochondrial abnormalities culminate in a reduced capacity of the mtGSH to control mROS accumulation