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In fact, people who have B12 deficiency are at higher risk of megaloblastic anemia, which essentially means the body does not have the ability to make enough red blood cells to carry oxygen through the body and leads to chronic fatigue

In some patients, using biotin alone may trigger a recurrence of the acute crisis, so biotin is usually combined with thiamine [67]

After 2 weeks, increase the dose to 20 mg/day

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