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Children can be prescribed a starting dose of 1mg, up to 5mg of melatonin per day and no serious side effects have been identified in studies of children

PMID: 27016292

The observed synergy in the Se 3 -I 0.4 treatment likely arises from this complementary action that selenium directly quenches ROS and may upregulate enzyme expression, while iodine primes the plants defense system through hormonal signaling

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EC demonstrates relatively low and variable oral bioavailability due to rapid phase II conjugation in the small intestine and liver, coupled with extensive microbial degradation in the colon (Oketch-Rabah et al., 2020)