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Synthesis of Amodiaquine Quinoneimine (AQ-QI) and Desethylamodiaquine Quinoneimine (DEAQ-QI) Synthesis of AQ-QI and DEAQ-QI was adapted from a method published previously, with a few modifications ( in vacuo and then applied to a silica-60 column to remove the tracing AQ or DEAQ

It is characterized by the acute onset of jaundice in the context of ongoing alcohol use, most commonly defined by a Maddreys discriminant function 32 or a model for end-stage liver disease score 20

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