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Choi JS, Lee SJ, Christ GJ, Atala A, Yoo JJ

Supports anti-inflammatory responses to reduce tissue damage

Etesian: a phase 2B study of the efficacy, safety and tolerability of AZD8233, a PCSK9-targeted antisense oligonucleotide, in patients with dyslipidemia [abstract]

CD4 + CD25 + Foxp3 + Tregs cell dysfunction is common in autoimmune diseases (199), and it may be converted into pathogenic Th17 cells after repeated amplification (200)

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This progressive neurodegenerative disorder is characterized by distinct pathological features, including the accumulation of iron in the substantia nigra pars compacta (SNc) and the aggregation of -syn within Lewy bodies, ultimately leading to the degeneration of dopaminergic neurons [2, 3]