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Deficiency symptoms often manifest as hair thinning, brittle texture, and premature greying, as B12 is necessary for melanin production in hair follicles

Once outside the cell, glutathione (GSH) degradation occurs exclusively in the extracellular space, and only on the surface of cells that express the ectoenzyme -glutamyl transferase

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Apoptosis-related regulatory molecules are activated when the cell receives an internal or external apoptotic signal