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6,8 However, studies have documented its use in this population without major side effects

Increase (), no significant change (), = modest decrease (improvement), = larger decrease (greater improvement)

Although inflammation can be a protective response, sustained activation of neuroinflammatory pathways leads to neuronal injury and causes the progression of neurodegenerative disorders ( 2.5 Impaired protein degradation systems Dysfunction in systems responsible for protein degradation, such as the ubiquitin-proteasome system (UPS) and autophagy, contributes to the development of AD and PD

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Moreover, sex steroids affect the development of HT in women