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doi: 10.1093/ajcn/54.2.377

Such a mechanism may explain the peptide's ability to enhance healing without causing excessive or dysregulated tissue growth, as its effects remain dependent on physiological growth factor signaling that is naturally upregulated during injury and repair processes

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The main reasons that have been put forward to explain the lack of success in trials with motilin agonist drugs for gastroparesis have been the use of too high doses, which impact on gastric accommodation, and the use of long-acting agents which are prone to desensitization (103)