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doi: 10.3390/v12010066 59 Otulak-KozieK.KozieE.PrzewodowskiW.CiackaK.PrzewodowskaA

The activities of manganese superoxide dismutase and glutathione-S-transferase, which detoxify superoxide and other electrophilic substances, respectively, are also inhibited by nitration (203, 346)

It accelerates the healing process of micro-damaged skin, reduces chronic redness, and strengthens the skins defense against environmental aging (UV, pollution, stress)

Hypoxic tumor microenvironment activates GLI2 via HIF-1 and TGF-2 to promote chemoresistance in colorectal cancer

Ideal for all skin types, it delivers an instant glow, leaving your complexion visibly brighter and more youthful

Acknowledgements We thank the Research Support Center for Human Disease Models, Graduate School of Medicine, Kyushu University, for technical assistance