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By dampening NMDA activity, DSIP reduces the mental hyperarousal that keeps you awake despite physical exhaustion

10.1016/s0014-2999(00)00542-2 8 AnderssonH.DemaegdtH.JohnssonA.VauquelinG.LindebergG.HallbergM.et al (2011)

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Research indicates that DSIP has a stress protective effect by modulating the activity of GABA in the brain