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According to the World Health Organization and the International Committee for Monitoring Assisted Reproductive Technology, infertility is a reproductive system disease defined as the failure to achieve clinical pregnancy after 12 months or more of routine unprotected sex ( via semen analysis, including determination of the sperm concentration/total number, motility, and morphology ( Genetic abnormalities can lead to spermatogenic disorders and account for 1530% of male infertility ( Chemical elements play important roles in male reproduction because imbalance of micronutrients or macronutrients may lead to spermatogenesis defects and decreased libido, resulting in male infertility

Phase 2: Adequate protein and amino acids (glycine, taurine, glutamine), sulfur-rich foods, methyl donors (folate, B12, choline), and glutathione support

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This indicates that the PPP has an important role in antibody production, likely by maintaining redox homeostasis during a time of heightened oxidative metabolism

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