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The increase is driven by the need for bone replacement and reconstruction of fractured and tumor bone, as well as rising prevalence of chronic osteoarthritis condition, and osteoporosis due to aging

Chem Biol 15:234245 Wewer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L et al (2012) Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Lab results: Attach serum magnesium level reports confirming hypomagnesemia

Nevertheless, there is an enormous need for awareness of HS, understanding of its pathogenesis and novel treatments

2013;5:a008672

* Correspondence: Jie Li [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers