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In addition to these treatments, many patients benefit from a comprehensive rehabilitation program that includes strengthening exercises, flexibility training, and education on proper body mechanics

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Compound 22 , a hybrid with the N-terminal from 21 and the C-terminal from 16 demonstrated a further enhanced potency (Ki = 23 nM) and a high selectivity for IRAP over AP-N (Andersson et al., 2010)

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In some embodiments, the otic formulation or composition comprises about 0.07% by weight of the viscosity modulating agent(s)

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