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Common neurological symptoms include: Paraesthesia (pins and needles) in the hands and feet Numbness or altered sensation Difficulty walking or balance problems (sensory ataxia) Muscle weakness and reduced coordination Cognitive changes , including memory problems, confusion, or difficulty concentrating Mood disturbances , such as depression or irritability In severe cases, vitamin B12 deficiency can cause subacute combined degeneration of the spinal cord, a serious condition affecting both sensory and motor pathways

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Vitamin B12 may affect certain inflammatory pathways, which can influence how your skin responds

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Excess circulating glucose is often deposited as fat in the liver and around visceral organs