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Thus, a GSTP1-G6PD-SRC complex might allow this metabolic signalosome to orchestrate responses of cancer cells to diverse forms of metabolic stresses typified by glucose deprivation and, with a lactic acid-triggered mechanism, facilitate biomass building and redox (re)balance to support robust cell proliferation (Graphical Abstracts)

doi: 10.1186/s12902-023-01286-6 211 ElciEKayaCCimNYildizhanRElciGG

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16 Interestingly, one patient had some abnormal changes in the elastic fibers and another patient had some excess of elastic fibers