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Preliminary results from animal studies and human cell culture studies suggest that therapies which increase telomerase activity and lengthen telomeres hold the key to life extension and reducing the rate of aging.68 Glutathione levels have been shown to parallel telomerase activity, which is an important indicator of life span

PMID 16236961

doi: 10.3389/fimmu.2025.1722463 Received 10 October 2025 Revised 03 December 2025 Accepted 12 December 2025 Published 12 January 2026 Volume 16 - 2025 Edited by Gabriella dEttorre, Sapienza University of Rome, Italy Reviewed by Christina K

The non-enzymatic antioxidant defense pathway, in particular, uses antioxidant or redox metabolites containing ascorbic acid (AsA), glutathione (GSH), and NADPH to reduce the excessive accumulation of ROS

Based on the lack of availability of EHR data, we conducted testing of the combined cohort (MA and FFS) in the ( claims-only version of the HWR measure

doi: 10.1016/j.trsl.2020.07.012 101 HoseinzadehA.Ghoddusi JohariH.AnbardarM