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PubMed Seredenin, S.B., Kost, N.V., & Voronina, T.A

10.1038/nrm.2017.89 158 ReubenJ

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Yes, in some cases, HER2 status can change as the disease evolves or after treatment, meaning a tumor may later test as HER2-negative or show reduced HER2 expression

(4) the method has simple and easily-controlled process parameters and stable product quality, is suitable for standardized industrial production, and is verified that the prescription and the process of the reduced glutathione for injection prepared by the invention are suitable for the requirement of large-scale production