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Furthermore, the expression levels of two trichothecene biosynthesis genes, Tri5 and Tri6 , were investigated by qRT-PCR

A-76 Grazulis 1993, p

Serum transaminase ALT/AST activities, IL-1, IL-1, and HMGB1 concentrations were drastically reduced by MeCbl treatment (Fig

: Intraperitoneal IFN-: Interferon gamma iNOS: Inducible nitric oxide synthase IS: Immobilization stress IB: Inhibitor of B KAT: Kynurenine aminotransferase KMO: Kynurenine-3-monooxygenase Kyn: Kynurenine L-AAA: L--aminoadipic acid LPS: Lipopolysaccharide MAO: Monoamine oxidase MAPK: Rasmitogen-activated protein kinase MDA: Malondialdehyde MDD: Major depressive disorder miR-134: MicroRNA-134 miRNAs: MicroRNAs MPO: Myeloperoxidase MyD88: Myeloid differentiation primary response 88 NE: Norepinephrine NMDAR: N-methyl-D-aspartate Receptor NSFT: Novelty-suppressed feeding test OFT: Open field test p.o

In this regard, orthogonal cytokine systems based on the IL-2/IL2-R interaction have been engineered and preclinically tested on Tregs with encouraging results