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Cardiolipin can be oxidized by ROS or by the cardiolipincytochrome c complex (Kagan et al., 2005)

in DMSO)

The present review revisits the foundational enzymology of HCU in the context of modern genotype-phenotype insights and incorporates novel epidemiological data quantifying the healthcare burden of classical HCU

In addition to this, exercise increases the oxidative capacity of liver mitochondria, which in turn improves the IR that drives hepatic steatosis

This provides a great premise for reconstructing haplotyped methylomes, for allowing insights on allele-specific 5mC patterns and their effects on mutations and gene regulation, while also being able to provide epigenetic information about repeat-rich regions [25, 30, 49]

In vitro findings highlighted the efficacy of DP in suppressing inflammation, ferroptosis, and oxidative stress via activation of Nrf2pathway