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In Utero Exposure to Simvastatin Reduces Postnatal Survival and Permanently Alters Reproductive Tract Development in the Crl:CD(SD) Male Rat

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(2015) established that fluorescein isothiocyanate (FITC)-dextran of 4 kD freely diffused through the GVB, whereas FITC-dextran of 70 kD could not, whereas infection with Salmonella enterica disrupted GVB and promoted 70 kD FITC-dextran crossing GVB

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Claiming oral equivalence to injection on the basis of gastric stability alone skips several critical steps in the pharmacokinetic argument