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Once the tumor volume reached approximately 50 mm 3 , the tumor-bearing mice were randomly divided into six groups ( n = 8) for treatment via intravenous injection as follows: (1) Control, (2) FeOOH, (3) DMOS@FeOOH, (4) GA-DMOS@FeOOH, (5) ICB, (6) ICB + GA-DMOS@FeOOH (combined therapy)

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Association of misfolded -synuclein derived from neuronal exosomes in blood with Parkinsons disease diagnosis and duration

Behavioral observation In a quiet environment, the mice were put into a round glass container at the bottom of the open field box, and the movie was taken and timed for 5 min at the same time