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Only after those validated approaches have genuinely been exhausted would DSIP even enter an educational discussion and even then, the framing has to remain that the evidence is weak

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Two other studies also indicated that 6 months supplementation with 2 mg/d folic acid, 25 mg/d vitamin B6, and 400 mg/d B12 had favorable effects on homocysteine, disability, and severity of migraine attacks (54, 60)

It is also under study in preclinical and animal models

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