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2, along with the main genera of Pseudomonadota involved in the processes

The value of selenium upon glutathione peroxidase 1 activity and oxidative stress mitigation in SARS-CoV-2 infection and COVID-19 disease has been clearly emphasized recently (Seale et al., 2020

The increased generation of free radicals in the hyperglycemic state may lead to the production of advanced glycation end products and the peroxidation reaction in lipids and protein

In this regard, pyrimidine biosynthesis is also controlled downstream of mTORC1, via S6K1-mediated phosphorylation of CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, dihydroorotase), the rate-limiting enzyme catalyzing the first three steps in the pyrimidine biosynthesis pathway (Robitaille et al., 2013)