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Kidney problems: People with preexisting kidney problems may experience worsened kidney function due to dehydration caused by diarrhea, nausea, or vomiting

Authors' contributions YW wrote the manuscript, conceived the topic of review and collected the data

Targeting NOS1 either through Hsp90 inhibitors to block its mitochondrial localization or via specific inhibitors such as N-propyl-L-arginine may offer dual benefits: mitigating therapy resistance and addressing metabolic risk factors in CRC (57, 58)

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DJ-1/PfpI domain containing proteins in Dicots Out of 217 DJ-1 protein members, one hundred and seven proteins were found to be present in dicots (Table 1)

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