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In fact, as a NO-dependent post-translational modification of proteins, S-nitrosothiols levels have been used as an indicator of NO production in biological samples and are known to increase upon infusion with sodium nitrite [140], nitrate ingestion [141], treatment with NO-releasing aspirin [142], and dietary flavonoid consumption [143]

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Efficient conversion in Fat-1 controls low levels of n-6/n-3, which support OL generation during remyelination, although in part through regulation of microglial inflammation 115

Antioxidants neutralise these free radicals, helping to prevent cellular damage and protect the integrity of the skin