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Recent advances in parasite biology suggest a compartmentalization of redox metabolism [5] as well as of cellular processes that are sites of drug action [6]

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The direct infusion of glutathione via IV can enhance its bioavailability, delivering the compound more effectively to where its most needed in the body

These suggest that iPLA2 can inhibit ferroptosis by eliminating ALOX12-induced lipid peroxidation

each one depletes glutathione through a direct biochemical mechanism