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At the same time, oxidative stress markers dropped by about 35%, and immune activity improved significantly

In our model, cells primed with Exendin-4 presented higher glycolytic rates when returned to culture media in the absence of GLP-1R stimulation

10.1038/nature09816 Nature 56 Gonzlez-MontelongoM

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It also interfaces with intracellular signaling networks connected to oxidative balance and cellular stress-response mechanisms