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Additional advancements in the prevention and management of underlying conditions may be required to significantly decrease mortality rates associated with sepsis (Rhee et al., 2019)

Van Schependom J, Dhaeseleer M (2023) Advances in neurodegenerative diseases

Additionally, the energy crisis induced by IRI is closely linked to impaired NAD+ biosynthesis [43]

A double-blind, randomized, placebo-controlled trial demonstrated that perioperative high-dose intravenous injection of Gln (0.5 g/kg/day, P.O for 3 days) raised plasma Gln concentrations and maintained plasma GSH levels in postoperative patients undergoing cardiopulmonary bypass (CPB) [113]