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Hashimoto, H., Takeuchi, M

Tulchinsky TH, Varavikova EA, Cohen MJ

Vitamin D: The Master Regulator Often called the "sunshine vitamin," Vitamin D actually acts more like a hormone, influencing over 200 genes throughout the body

Skin regeneration + wrinkle formation

The main bias in the association between irAEs and clinical outcomes is the immortal time bias (ITB)

The promise of targeting this pathway is underscored by findings that iron chelation therapies can lower nigral iron levels and provide neuroprotective effects (Jiang et al., 2017