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This indicates that the drug resistance of DTP cells is a dynamic, non-genetic adaptive change (49) (Table 2)

10.1016/j.canlet.2015.12.002 162 JiangH.YangX.MiM.WeiX.WuH.XinY.et al (2021)

In the presence of UVR, reduced folates may undergo irreversible oxidative cleavage into by-products of pteridine and p-aminobenzoylglutamate, both of which lack vitamin activity