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The doses of mitragynine (1 and 30 mg/kg) were given intraperitoneally

The outcome was a decrease in tremor frequency after both interventions, probably because tremor was secondary to abnormal peripheral mechanical reflex mechanisms [ 75 ]

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In such cases, MMA concentrations in urine should be adjusted for creatinine excretion (Norman & Morrison, 1993) and the ratio of urinary MMA to creatinine (uMMA/C) applied to assess B12 status