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In addition, MSCs could secrete a large number of bioactive molecules that potentially affect immune and inflammatory reactions

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Lee HY, Back K (2016b) Mitogen-activated protein kinase pathways are required for melatonin-mediated defense responses in plants

Other potential causes such as polycythemia, chronic obstructive, or interstitial lung disease, and neurological dysfunction must be ruled out before confirming a diagnosis of HAPH [3]