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Mitophagy inhibits amyloid- and tau pathology and reverses cognitive deficits in models of Alzheimers disease

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Blood and tissue processing For all studies blood was drawn by cardiac puncture in anesthetized mice and collected in 5 l EDTA (BD medical) before being spun in a microcentrifuge at 9.8 revolutions per minute (RPM) for 5 min at room temperature

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Acetyl L-carnitine, however, is more easily taken up by the intestines and the muscle cells, not to mention the brain, in the absence of food