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Free Radical Biology and Medicine 2007;43(12) 1649-1655 183

Jepson MM, Bates PC, Broadbent P, Pell JM, Millward DJ

& Mottes, M

In normal physiology, Ca 2+ acts as a second messenger when released from the ER, triggering the exocrine secretion of zymogen granules (ZG) and promoting ATP production in mitochondria (23, 42)