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Luminescence was measured on an EnSpire Alpha (Perkin Elmer) using the integrated software package

The supplement also improved two functional biomarkers in urine, FIGLU and methylmalonic acid, indicating the supplement decreased the need for folic acid and vitamin B12, respectively

Metagenomic and metabolomic analysis showing the adverse risk-benefit trade-off of the ketogenic diet

Cells were incubated with a mouse monoclonal antibody targeting the human transferrin receptor (Clone H68.4, #136800, Invitrogen, Eugene, OR) diluted to a final concentration of 2 g/mL in PBS overnight at 4 C

Whenever possible, I prioritized human studies

Except for inhibiting oxidative stress-related signaling pathways mediated by Apos, other antioxidative properties of Apos that interact with oxidant and LDL oxidation byproducts are well established