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10.1172/JCI124049 92 HuangW.ChenK.LuY.ZhangD.ChengY.LiL.et al (2021)

But only the R-isomer (R-ALA) is naturally produced in the body and actively participates in mitochondrial energy metabolism.12 Some studies suggest that R-ALA may be more bioavailable than standard racemic ALA though the clinical significance of this difference is still under investigation.17 In addition, anecdotal reports and small studies indicate that R-ALA may be easier on digestion, with fewer gastrointestinal side effects than standard racemic ALA, especially at higher doses.18 However, R-ALA is chemically unstable on its own

Think of the chelating agent as a magnet or claw that attaches to toxic metals in your blood

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