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the balance being an aqueous based carrier

Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: circumvention studies using novel platinum (II) and (IV) ammine/amine complexes

and 54% had a baseline KPS score of 90-100% and 46% had a KPS score of 70-80%

Given the resistance of EGFR-altered tumors to conventional EGFR inhibitors, ongoing research into combination therapies and novel targeted approaches remains critical for improving treatment efficacy in EGFR-mutant GBM

Dickerson F, Adamos M, Katsafanas E, Khushalani S, Origoni A, Savage C, et al

The enzymes that execute this backstop are encoded by GSTM1 and GSTT1 , two members of the glutathione S-transferase family