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DISSECTION P2398 - ESOC25-1847 CEREBROCERVICAL ARTERY DISSECTION AS THE UNDERLYING CAUSE OF ACUTE ISCHEMIC STROKE: A PROSPECTIVE TEN YEAR STUDY Maria Chondrogianni 1 , Aikaterini Foska 1 , Athanasios Tsibonakis 1 , Aikaterini Theodorou 1 , Georgia Papagiannopoulou 1 , Konstantinos Melanis 1 , Klearchos Psychogios 2 , Odysseas Kargiotis 2 , Apostolos Safouris 2 , Eleni Bakola 1 , Maria Ioanna Stefanou 1 , Stefanos Lachanis 3 , Georgios Velonakis 4 , Lina Palaiodimou 1 , Georgios Tsivgoulis 1,5 1 Second Department of Neurology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, 2 Stroke Unit, Metropolitan Hospital, Piraeus, Piraeus, Greece, 3 Iatropolis Magnetic Resonance Diagnostic Centre, 15231, Athens, Greece, 4 Second Department of Radiology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, 5 Department of Neurology, University of Tennessee Health Science Center, Memphis, United States Background and Aims: Cervicocerebral artery dissection (CAD) accounts for nearly 2% of acute ischemic strokes (AIS), but this rate increases up to 25% in young ( 6 months)

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209 Some human-based defense peptides such as human -defencins (hBDs), dermcidins and cathelicidin LL-37are well known for promoting wound healing in chronic conditions