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Additional technologies used antenatally, which have led to improvement in outcome, include antenatal blood group genotyping by polymerase chain reaction from fetal cells obtained by amniocentesis or even from maternal blood samples.24,128 Assessment of the degree of fetal anemia and determination of the need for intrauterine transfusion noninvasively, by determining middle cerebral artery peak systolic velocity by Doppler technique, has reduced the need for invasive procedures

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