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Its also critical for brain development and maintaining a healthy nervous system

Elife 3 , e03245 (2014)

Similar to the reduced homeostatic capacity of adult tracheal cells after Sox2 ablation (Que et al , 2009), we found depletion of AQP5 + acinar cells after ablation of Sox2 in SOX2 + acinar progenitors under both homeostatic and damage conditions