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The absence of biotin affects the expression of transcription factors like NF-B and SP1/3, indicating that biotin regulates immunological phenomena via mechanisms besides carboxylation and decarboxylation (152) ( Table 2 )

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doi: 10.3389/fnut.2023.1288749 39

& Dillon, M

This is especially important if you experience symptoms commonly associated with high vitamin B12 levels in the blood, including: 9 Gastrointestinal issues, such as nausea, vomiting, or diarrhea Headaches Tingling sensations in the hands and feet Weakness and fatigue Should I Be Concerned About High Vitamin B12 Levels