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188 ARG2 has also been reported to promote melanoma tumor metastasis through the H 2 O 2 -STAT3 pathway (Fig

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On the other hand, DAM can also exert neuroprotective functions through TREM2 signaling, as evidenced by the finding that TREM2 deficiency exacerbates pathological TDP-43 inclusions, motor dysfunction, and neurodegeneration (Xie et al., 2022)

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Finally, compared with full-term infants, preterm infants had 2.5 higher sulfur AAs levels and 1.7 higher levels of taurine, a cysteine-degradation product, in venous cord blood, with the highest levels in NAC-treated moderate IPTB cases (see details in legend Supplementary Table S5)

As mentioned earlier, cytochrome P450 (Cyp450) plays a major role in the detoxification process of APAP