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doi: 10.1093/infdis/jiz325 145 WangW.ZhangX

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It is important to note that this depletion is unlikely to be attributed to colitis-associated nutrient absorption defects, as B 12 is typically absorbed in the terminal ileum 26 , while DSS primarily affects the distal colon 61

However, the literature is not uniformsome reports show androgen-associated functional impairment rather than simple hyperactivationunderscoring that androgen effects depend on dose, timing, and the systemic inflammatory milieu [36]