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The resultant oxidative stress adversely impacts cochlear homocysteine metabolism, suggesting a potential link between Vitamin B12 deficiency and demyelination of neurons in the cochlear nerve, axonal degeneration, and neuronal death

Cell Death Dis 7(12):e2511 Lee YM, Lee G, Oh TI et al (2016b) Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress

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Therefore, whatever influence GSH depletion has on the structures of the capsid related particles this does not prevent normal association of 2C ATPase /replication complex with the VP3 polypeptide contained in these particles

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