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Nanoformulations of curcumin: an emerging paradigm for improved remedial application

J Biosci Bioeng 130:630636

Evidence is mixed and inconsistent

Both options are safe when used correctly

As the target can be located in intracellular compartment of the brain parenchyma, the main determinant of successful application of the approach for delivery of drugs with the brain parenchymal intracellular targets is an improvement of unbound steady-state concentrations of released parent drug in intracellular compartment in comparison to parent drug dosing