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282 , H281H291 (2002)

The E6 protein binds to and promotes the degradation of the tumor suppressor protein p53, inhibiting apoptosis and enabling the accumulation of genetic mutations, and it can also activate telomerase, contributing to cellular immortality

Perisic L, Aldi S, Sun Y, Folkersen L, Razuvaev A, Roy J, Lengquist M, kesson S, Wheelock CE, Maegdefessel L, et al

-Glutamylcyclotransferase as a novel immunohistochemical biomarker for the malignancy of esophageal squamous tumors

TERT promoter mutation Mutations in the promoter region of the TERT gene have emerged as key molecular alterations in gliomas, influencing tumor progression, prognosis, and treatment response

[] A summary of all clinically proven natural products described in this study is provided in Table 1